When should I take fenofibrate morning or night?
Mar 22, · Fenofibrate is used along with a proper diet to help to treat high cholesterol and high triglyceride levels. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help fenofibrate work better include exercising, losing weight if overweight, and stopping manuelacosplay.us names: Triglide, Lipofen, Antara, Tricor, Fenoglide. Dec 20, · Fenofibrate comes in two forms: oral tablet and oral capsule. Fenofibrate oral tablet is used to treat high cholesterol levels. It’s mainly used to treat severe high triglycerides (a type of bad Estimated Reading Time: 7 mins.
Drug information provided by: IBM Micromedex. Use this medicine only as directed by your doctor. Do not use more of it, do not takne it more often, or do not use it for a longer time than your doctor ordered.
In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. Carefully follow your doctor's order about any special diet for this medicine to work well. If you have excess body weight, your doctor may tell you to exercise to lose taekn weight before using this medicine. Also avoid take alcohol before fdnofibrate during treatment with fenofibrate. This medicine is usually taken once a day.
Take the medicine at the same time each day to maintain the medication's effect. Do not open, crush, break, chew, or dissolve them. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, take it as soon as possible.
However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
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Jul 01, · Fenofibrate is only part of a complete program of treatment that also includes diet, exercise, and weight control. Avoid drinking alcohol while taking fenofibrate. Alcohol can raise triglyceride levels, and may also damage your liver while you are taking fenofibrate. Fenofibrate is used with dietary modifications for the treatment of lipid disorders. It helps reduce levels of LDL-C, total cholesterol, triglycerides, and apolipoprotein B, and increase HDL -C. It is prescribed to patients with primary hypercholesterolemia or mixed dyslipidemia, and hypertriglyceridemia. Background: Fenofibrate has been used for the management of atherogenic dyslipidaemia for many years. Reports of fenofibrate-associated increases in serum creatinine (SCr) levels raised concerns regarding deleterious effects on renal manuelacosplay.us by:
Medically reviewed by Carmen Fookes, BPharm. Last updated on Jan 27, If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:. Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects.
View complete list of side effects. Medicines that interact with fenofibrate may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with fenofibrate. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Note that this list is not all-inclusive and includes only common medications that may interact with fenofibrate.
You should refer to the prescribing information for fenofibrate for a complete list of interactions. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use fenofibrate only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Patient Tips fenofibrate Print Save. How it works Fenofibrate may be used in the treatment of high cholesterol. Fenofibrate activates an enzyme called lipoprotein lipase which increases the breakdown of lipids and the elimination of triglyceride-rich particles from the blood. Fenofibrate belongs to the class of medicines called fibrates.
Upsides May be used to treat high cholesterol dyslipidemia. Can be a good alternative for people who can't tolerate statins. Should be used in addition to a healthy diet.
Fenofibrate is more effective than statins at increasing HDL cholesterol levels, similar to atorvastatin and rosuvastatin at reducing triglyceride levels, but less effective than statins at lowering LDL cholesterol levels. Available as oral tablets and oral capsules. Generic fenofibrate is available. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Abdominal pain, a headache, backache, nausea, constipation, nasal congestion or a runny nose.
Fenofibrate has been associated with myopathy dysfunction of muscle fibers and rhabdomyolysis muscle cell destruction. The risk is increased in seniors and in people with diabetes, kidney disease, hypothyroidism, and also in those taking statins or colchicine.
Tablets may need to be discontinued if serious muscle problems occur. Has not been shown to reduce the risk of death from heart disease in patients with type 2 diabetes. Dosage may need to be reduced in people with mild-to-moderate kidney disease. Not recommended for people with severe kidney disease. May cause an increase in liver enzymes. Liver enzymes need to be periodically monitored and fenofibrate should be discontinued if liver enzymes reach three times the upper limit of normal.
In some people, fenofibrate may severely depress HDL cholesterol levels. HDL levels should be checked within the first few weeks of fenofibrate therapy and the drug discontinued if HDL cholesterol levels have dropped significantly. May not be suitable for some people including those with gallbladder disease, liver disease, severe kidney disease and in women who are pregnant or breastfeeding.
May interact with some drugs including warfarin may prolong bleeding times , sulfonylureas, statins, colchicine, bile acid binding resins, and immunosuppressants. View complete list of side effects 4. Bottom Line Fenofibrate is effective at reducing triglyceride levels and increasing HDL cholesterol levels; however, it is less effective than statins at reducing LDL cholesterol levels. Tips Can be given with or without food. Use in addition to an appropriate lipid-lowering diet and regular exercise.
Reducing body weight and alcohol consumption will also help lower cholesterol and triglyceride levels. Report promptly any unexplained muscle tenderness, weakness or pain, especially if other symptoms such as fever or feeling unwell are also present. Seek urgent medical attention if you develop symptoms of an allergic reaction such as difficulty breathing, swelling, or a rash or yellowing of the skin or eyes while taking fenofibrate.
Diseases such as hypothyroidism low thyroid levels and diabetes contribute to dyslipidemia, so it is important these are treated as well. In addition, some medications for example, estrogen, bendroflumethiazide, and atenolol may increase triglyceride levels. Your doctor should consider discontinuing therapy if you have not had an adequate response after two months of treatment.
Response and Effectiveness Fenofibrate is quickly absorbed and converted into its active ingredient fenofibric acid once inside the body. Takes about a week for levels to stabilize. May take several weeks before effects on cholesterol and triglycerides levels are apparent. Cholesterol and triglyceride levels should be monitored every four to eight weeks.
Dosage should be individualized according to response. Interactions Medicines that interact with fenofibrate may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with fenofibrate.
Common medications that may interact with fenofibrate include: acyclovir aminoglycosides, such as gentamicin or neomycin beta-blockers, such as atenolol or sotalol black cohosh colchicine cancer medications, such as cisplatin or pemetrexed cholestyramine cyclosporine diabetes medications, such as insulin, glimepiride, glipizide, or glyburide diuretics, such as HCTZ or chlorthalidone ezetimibe leflunomide other lipid-lowering drugs such as atorvastatin or simvastatin raltegravir red yeast rice ursodiol warfarin Alcohol may make fenofibrate treatment less effective.
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